Marqueur diagnostique pour le cancer

Diagnostische marker für krebs

Diagnostic marker for cancer

Abstract

Es wird die Verwendung verschiedener Proteine als diagnostische Marker für Krebserkrankungen bereitgestellt. Besonders bevorzugt ist die Verwendung des Proteins Annexin A3. Bevorzugterweise wird hierbei eine Heraufregulation von Annexin A3 im Vergleich mit Kontrollen untersucht. Weiterhin wird die Verwendung von Wirkstoffen zur Herstellung eines Medikaments zur Behandlung von Krebs beschrieben, wobei diese Wirkstoffe die Aktivität und/oder die Abundanz verschiedener charakteristischer Proteine beeinflussen.
The invention relates to the use of various proteins as diagnostic markers for cancerous diseases. In particular, the use of the annexin A3 protein is preferred. Preferably an increased regulation of annexin A3 is analysed in comparison to controls. The invention also relates to the use of active substances for producing a medicament used in the treatment of cancer, said substances influencing the activity and/or abundance of various characteristic proteins.
L'invention concerne l'utilisation de diverses protéines comme marqueurs diagnostiques pour des maladies cancéreuses. On mentionne, de préférence, plus particulièrement l'utilisation de l'annexine A3. De préférence, une régulation accrue de l'annexine A3 est analysée en comparant avec des témoins. L'invention concerne en outre l'utilisation de substances actives pour la production d'un médicament pour le traitement du cancer, lesdites substances actives influençant l'activité et/ou l'abondance de protéines caractéristiques variées.

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